Major Autohemotherapy (MAH)

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Ozone is widely used as an alternative medicine, although its safety and efficiency are met with some contrary opinions and scepticism. A lot of methods are developed, such as EBOO, Major autohmotherapy, or local injections. In this article we would like to give you a better understanding about Major autohemotherapy, Chai Natural Clinic tried to summarize the effect of ozone-autohaemotherapy for you.

The Initial Process of Major Autohemotherapy

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Autohemotherapy works with mixing a small amount of the patient bloods with ozone. The oxygen/ozone gas mixture, containing a total of 14.75 mg of ozone (59 f1g OJ/ml of blood). is rapidly added with gentle mixing, after which the blood is slowly reinfused into the donor. Using this procedure, hemolysis is expected to not exceed 2.B ± 0.7% and intraerythrocytic-reduced glutathione decreases no more than about 8%. To ease the process, a heparin will be included in the therapy. Patients who are hypersensitive to heparin, under anticoagulant therapy, or prone to the haemorrhagic syndrome should be given autohemotherapy simply using citratephosphate-dextrose.

Medical ozone mixed with blood produce hydrogen peroxide (H2O2), which triggered as an important messenger in activating the immunity system. Process of ozonation in blood is characterized by the formation of only few molecules of reactive oxygen species (ROS) and lipid oxidation products (LOP) acting in two phases : while ROS ( mainly hydrogen peroxide) are acting immediately and disappear (early and short-acting messengers), LOPs (late and long-lasting messengers).

Ozone therapy is helping to initiate a series of chemical reactions, inducing the production of interleukin and interferon and other cytokines to activate and regulate the immune system function, and, finally, restore the normal functioning of the thalamus for the pain loop

Side Effects of Autohemotherapy

Autohemotherapy appears to be a all-in-one to do therapeutic approach acting in various different diseases by virtue of the effects of ozone treatment on several blood components, which, after treatment, induce metabolic changes and release various cytokines. Ozone autohemotherapy has been standard and clinical study for almost 40 years and has become a relatively mature method of clinical treatment.

Benefits of Autohemotherapy

Ozone Autohemotherapy has benefits as healing-booster capabilities as well as anti-inflammatory effects within the body. It also increases energy, circulation, eases pain in certain injuries, and overall boosts the immune system which helps in a patient’s overall health. Nowadays, ozone auto-hemotherapy is reported as being mainly used for the therapy of viral hepatitis, hyperlipidemia, stroke, rheumatic diseases, insomnia, and cancer.

Diseases to be Treated with Autohemotherapy

Based on Bocci’s research journal (1994), the following four main categories of diseases may benefit from the treatment:

1. Vascular disorders from critical limb to heart, brain and retinal ischaemia.

Autohaemotherapy was reported to have positive results from those who suffered cardiovascular disease.

During ozone therapy, a clinical study from Suarez et.al. (2018), observed that most of the patients (66.7%) who were charged for physical limitation: no symptoms at rest, any physical activity causes the appearance of symptoms experiencing imprvement after the 15 sessions in 45 days. A significant change was observed, with 86.7% of patient improved to slight limitation of physical activity: without symptoms at rest, normal physical activity causes fatigue, palpitations or dyspnoea. The results that remained in progress throughout the year under treatment until reaching 53.3% of them to their best health condition, without limitation: normal physical exercise does not cause fatigue, dyspnoea or undue palpitation.

2. Chronic viral diseases

Favoured by immunodepression either due to genetic deficiency, or cytotoxic treatments and/or ageing.

3. Autoimmune diseases

At the moment it is considered that local release of either IFN r causing apoptosis of autocytotoxic T lymphocytes, or of immunosuppressive factors such as IL-10, TGF,8, IL-1f3-TNF a antagonists and eicosanoids may suppress reactive clones.

4. Minimal residual disease

As cancer kills the host mostly via metastasizing cells, it is necessary to eliminate them and immunotherapy.

On the basis of biochemical and clinical studies performed in the last two decades, it has become clear that ozone, in appropriate dosages, behaves as a real booster and the biochemical and molecular mechanism of action are well within orthodox medicine. 

However, to achieve that, minimizing blood cell damage during ozone treatment is of the utmost importance. As would be expected, there is a dose-effect relationship between ozone concentration, duration of exposure and the production of cytokines The biological response to ozone treatment varies widely between blood samples, not only because blood mononuclear cells of different individuals vary in their ability to respond to certain stimuli, but also because each blood sample has a variable level of antioxidants.

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